The Clinical and Cost-Effectiveness of 4 Enzyme-Linked Immunosorbent Assay Kits for Monitoring Infliximab in Crohn Disease Patients: Protocol for a Validation Study

Fri 19 October 18

Thomas Langford, MSc, Zehra Arkir, FRCPath, Anastasia Chalkidou1, MBBS, PhD, Kate Goddard, PhD, Lamprini Kaftantzi, PhD, Mark Samaan, MBBS, BSc, Peter Irving, MA MD FRCP

KiTEC produced a protocol for a study to support the research recommendations made in NICE DG22...

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SecurAcath for Securing Peripherally Inserted Central Catheters: A NICE Medical Technology Guidance

Mon 20 August 18

Tom Macmillan, Mark Pennington, Jennifer A. Summers, Kate Goddard, Darshan Zala, Naomi Herz, Janet L. Peacock, Stephen Keevil, Anastasia Chalkidou

This study describes KiTEC's work on completing an assessment report for SecurAcath,...

Evaluating the Diagnostic Accuracy of Reflectance Confocal Microscopy to Diagnose Skin Cancer: Protocol for a Prospective, Multicenter Study

Thu 09 August 18

Naomi D Herz, MSc, Anastasia Chalkidou, MD, PhD, Fiona Reid, MSc, Stephen F Keevil, PhD, FIPEM, FInstP, Andrew Coleman, PhD,...

The Future of Precision Medicine: Potential Impacts for Health Technology Assessment

Fri 13 July 18

JC Rejon-Parrilla, RE Lovett, A Chalkidou, J Love-Koh, H Wood, K Ennis, A Peel, M Taylor

A joint project between KiTEC...

A Systematic Review and Aggregated Analysis on the Impact of Amyloid PET Brain Imaging on the Diagnosis, Diagnostic Confidence, and Management of Patients being Evaluated for Alzheimer’s Disease

Tue 24 April 18

1,531 cases from 12 studies were analysed in this systematic review investigating the value of amyloid PET imaging in diagnosing...

Comparing the Diagnostic Accuracy of Simple Tests to Screen for Diabetic Peripheral Neuropathy: Protocol for a Cross-Sectional Study

Fri 06 April 18

This publication outlines the protocol for a cross-sectional study comparing 5 simple tests for diabetic peripheral neuropathy, including the VibraTip...

Bile Acid Diarrhoea: evidence for lower SeHCAT retention in type 3 patients following cholecystectomy

Mon 17 October 16

John McLaughlin, Robert Logan, Fiona Dorothy Alexandra Reid, Jennifer Summers

Introduction: Bile Acid Diarrhoea (BAD) is an under-recognised cause of chronic...

Virtual Touch Quantification (VTq) to diagnose and monitor liver fibrosis in Hepatitis B and C.

Wed 07 September 16

Kings Technology Evaluation Centre (KiTEC) published in Applied Health Economics and Health Policy a study as part of a NICE...

CT scanners for coronary CT angiography (CCTA) in challenging patient groups

Tue 05 July 16

This report discusses the technical approaches used to address the challenges of CCTA imaging and compares the relevant technical...

Multicentre prospective survey of SeHCAT provision and practice in the UK

Wed 25 May 16


A clinical diagnosis of bile acid malabsorption (BAM) can be confirmed using SeHCAT (tauroselcholic (75selenium) acid), a radiolabelled synthetic bile...

Diagnostic accuracy of (18)F amyloid PET tracers for the diagnosis of Alzheimer's disease: a systematic review and meta-analysis

Mon 01 February 16

Imaging or tissue biomarker evidence has been introduced into the core diagnostic pathway for Alzheimer's disease (AD). PET using (18)F-labelled...

A Multicenter Prospective Study to Investigate the Diagnostic Accuracy of the SeHCAT Test in Measuring Bile Acid Malabsorption: Research Protocol

Sat 02 January 16

Background: Bile acid malabsorption (BAM) is one possible explanation for chronic diarrhea. BAM may be idiopathic, or result from ileal...

The geko™ Electro-Stimulation Device for Venous Thromboembolism Prophylaxis: A NICE Medical Technology Guidance

Wed 01 April 15

The gekoTM device is a single-use, battery- powered, neuromuscular electrostimulation device that aims to reduce the risk of venous thromboembolism...

E-vita open plus for treating complex aneurysms and dissections of the thoracic aorta

Tue 04 June 13

The E‑vita open plus (JOTEC GmbH) is an endoluminal stent graft system designed for treating aneurysms and dissections of the...