NICE

MIB27 Prosigna

Prosigna is a prognostic gene signature assay that measures gene expression to calculate the risk of women with early-stage breast cancer developing distant recurrence 10 years from diagnosis. The assay measures the expression profiles of all 50 of the genes included in the PAM50 gene signature, and can be performed on RNA isolated from formalin-fixed, paraffin-embedded breast tumour tissue.

NICE page: https://www.nice.org.uk/advice/mib27